Treatment of Malaria: Qualaquin is indicated only for treatment of uncomplicated Plasmodium falciparum malaria. Quinine sulfate has been shown to be effective in geographical regions where resistance to chloroquine has been documented (See CLINICAL STUDIES).

Qualaquin oral capsules are not approved for patients with severe or complicated P. falciparum malaria.

Qualaquin oral capsules are not approved for prevention of malaria.

Qualaquin oral capsules are not approved for the treatment or prevention of nocturnal leg cramps.